Pathogenicity and transmissibility of 2019-nCoV-A quick overview and comparison with other emerging viruses.
Identifieur interne : 000517 ( Main/Exploration ); précédent : 000516; suivant : 000518Pathogenicity and transmissibility of 2019-nCoV-A quick overview and comparison with other emerging viruses.
Auteurs : Jieliang Chen [République populaire de Chine]Source :
- Microbes and infection [ 1769-714X ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- virologie : Infections à coronavirus, Pneumopathie virale.
- transmission : Humains, Infections à coronavirus, Nombre de reproduction de base, Pandémies, Pneumopathie virale, Virulence.
English descriptors
- KwdEn :
- MESH :
- pathogenicity : Betacoronavirus.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Basic Reproduction Number, Humans, Pandemics, Virulence.
Abstract
A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted.
DOI: 10.1016/j.micinf.2020.01.004
PubMed: 32032682
Affiliations:
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Electronic address: jieliangchen@fudan.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author></analytic><series><title level="j">Microbes and infection</title><idno type="eISSN">1769-714X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Basic Reproduction Number</term><term>Betacoronavirus (pathogenicity)</term><term>Coronavirus Infections (transmission)</term><term>Coronavirus Infections (virology)</term><term>Humans</term><term>Pandemics</term><term>Pneumonia, Viral (transmission)</term><term>Pneumonia, Viral (virology)</term><term>Virulence</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term><term>Infections à coronavirus (transmission)</term><term>Infections à coronavirus (virologie)</term><term>Nombre de reproduction de base</term><term>Pandémies</term><term>Pneumopathie virale (transmission)</term><term>Pneumopathie virale (virologie)</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Basic Reproduction Number</term><term>Humans</term><term>Pandemics</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="fr"><term>Humains</term><term>Infections à coronavirus</term><term>Nombre de reproduction de base</term><term>Pandémies</term><term>Pneumopathie virale</term><term>Virulence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Jieliang" sort="Chen, Jieliang" uniqKey="Chen J" first="Jieliang" last="Chen">Jieliang Chen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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